The Institute of Biomedical Engineering and Nanomedicine of National Health Research Institutes focuses on research areas of biomaterials and regenerative medicine, biomedical imaging, nano-medicine, and medical electronics; and it performs translational research in close collaboration with clinical institutions. The institute also forms close connections with local and international industrial players to enhance commercialization of its research products.

Achievements:
• Biomaterials and Regenerative Medicine
1.Development of biodegradable and injectable bone cement for femur head angiogenesis and regeneration.
2.Development of surface plasmon resonance technology for Chinese medicine and stimulative surface technology for tissue engineering, respectively.
3.Development of microfluidic hanging drop cell culture and single-cell culture techniques to miniaturize experiment setup and reduce cost.

• Biomedical Imaging
1.A high-gradient-strength human MRI system, which provides high resolution and accuracy to map the brain connectomics.
2.MR-guided focused ultrasound technology platform for non-invasive precision therapy.

• Nano-Medicine
1.Explore states of nano-objects in liquid environment by K-kit (a Si-based micro channel device) on electron microscopy.
2.Caged Pt nanocluster (NHRI-CPN) that can exert tumor-inside activation for anticancer chemotherapeutic with minimizing systemic toxicity is reported. The CPN has great potential to overcome cancers with cisplatin-like resistance, such as triple-negative breast cancer and lung cancer.
3.Implantable radioactive gold nanoparticles can inhibit unresectable brain tumor cells after surgery and enhance the efficacy of follow-up concurrent chemoradiotherapy (CCRT) to avoid recurrence.
4.Novel endogenous red blood cell-derived vesicles (RDV) as nanocarriers.
5.Nanoparticle-enhanced tropism of stem cells to cancer and other diseases for therapy.
6.A novel nanoplatform with X-ray activated photodynamic effect for molecular imaging-guided intensity modulated radiation nanotherapy to noninvasively treat deep-tissue cancers.